C16orf78

Across TCGA patient cohorts, C16orf78 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,807 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C16orf78-associated GO terms across cancer lineages are Heart morphogenesis, Cardiac ventricle development, and Regulation of canonical Wnt signaling pathway. Each is linked with C16orf78 in more than 20 cancer types. Because this analysis shows association rather than direction, both C16orf78-to-partner and partner-to-C16orf78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heart morphogenesis grouped by C16orf78-low versus C16orf78-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf78→partner) and Y-score (partner→C16orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Heart morphogenesis →	+0.052	+0.114	<.001	<.001	3	21
STAD	Cardiac ventricle development →	+0.049	+0.115	<.001	<.001	3	21
STAD	Regulation of canonical Wnt signaling pathway →	+0.062	+0.110	<.001	<.001	3	20
STAD	Response to endoplasmic reticulum stress →	+0.072	+0.120	<.001	<.001	3	20
STAD	TORC1 signaling →	+0.078	+0.111	<.001	<.001	3	20
STAD	Retrograde transport, endosome to Golgi →	+0.067	+0.120	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,807 associations by consensus.

Heart morphogenesis by C16orf78 expression — STAD

Explore this box plot interactively →