C16orf78

Across TCGA cell cohorts, C16orf78 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C16orf78-associated genes across cancer lineages are CABP5, OR1M1, and C3orf22. Each is linked with C16orf78 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf78-to-partner and partner-to-C16orf78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABP5 grouped by C16orf78-low versus C16orf78-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf78→partner) and Y-score (partner→C16orf78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CABP5 →	+0.008	+3.700	<.001	.009	3	1
SKIN	OR1M1 →	+0.010	+3.700	<.001	.009	3	1
SKIN	C3orf22 →	+0.035	+4.000	<.001	<.001	3	1
SKIN	KCNB2 →	+0.055	+4.070	<.001	.003	3	1
SKIN	MROH7 →	+0.291	+3.415	<.001	.009	3	1
SKIN	KRTAP29-1 →	+0.018	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CABP5 by C16orf78 expression — SKIN

Explore this box plot interactively →