C16orf72

Across TCGA cell cohorts, C16orf72 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,045 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C16orf72-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cell PML body, Regulation of proteasomal ubiquitin-dependent protein catabolic process, and Regulation of binding. Each is linked with C16orf72 in more than 18 cancer types. Because this analysis shows association rather than direction, both C16orf72-to-partner and partner-to-C16orf72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cell PML body grouped by C16orf72-low versus C16orf72-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf72→partner) and Y-score (partner→C16orf72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Symbiont-mediated disruption of host cell PML body →	+0.107	+0.710	<.001	<.001	3	19
LARGE_INTESTINE	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.058	+0.936	<.001	<.001	3	14
LUNG_SCLC	Regulation of binding →	+0.087	+0.440	<.001	<.001	3	13
OVARY	Host-mediated perturbation of viral process →	+0.067	+0.683	.003	.002	3	13
LUNG_NSCLC_LUAD	Negative regulation of organelle assembly →	+0.049	+0.549	.003	.006	3	13
OVARY	Positive regulation of mRNA catabolic process →	+0.068	+0.965	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,045 associations by consensus.

Symbiont-mediated disruption of host cell PML body by C16orf72 expression — OVARY

Explore this box plot interactively →