C16orf71

Across TCGA patient cohorts, C16orf71 mutation is significantly associated with the RNA expression of many other genes, with 2,237 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf71-associated genes across cancer lineages are RNA5SP412, PDP2, and OR6K6. Each is linked with C16orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf71-to-partner and partner-to-C16orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by C16orf71-low versus C16orf71-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf71→partner) and Y-score (partner→C16orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.899	+2.645	<.001	<.001	3	2
UCEC	PDP2 →	+0.551	+3.064	<.001	<.001	3	2
UCEC	OR6K6 →	+0.049	+2.551	<.001	.007	3	2
LUSC	SNORD114-13 →	+0.669	+4.625	<.001	.008	3	2
LUSC	ZNF736P6Y →	+0.036	+4.882	.008	.005	3	2
UCEC	MIR3661 →	+0.734	+2.353	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,237 associations by consensus.

RNA5SP412 by C16orf71 expression — UCEC

Explore this box plot interactively →