C16orf71

Across TCGA patient cohorts, C16orf71 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C16orf71-associated genes across cancer lineages are eEF2, Ku80, and Rictor_pT1135. Each is linked with C16orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf71-to-partner and partner-to-C16orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by C16orf71-low versus C16orf71-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf71→partner) and Y-score (partner→C16orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.410	+2.222	.006	.011	3	2
UCEC	Ku80 →	+0.313	+2.235	.001	.006	3	2
UCEC	Rictor_pT1135 →	-0.114	-2.459	.008	.019	3	2
UCEC	STAT5a →	+0.536	+3.321	.001	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.802	+3.479	.001	.002	3	2
UCEC	4E-BP1 →	+0.297	+2.199	.009	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

eEF2 by C16orf71 expression — UCEC

Explore this box plot interactively →