C16orf71

Across TCGA cell cohorts, C16orf71 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C16orf71-associated genes across cancer lineages are GGTLC2, PAX4, and SYT10. Each is linked with C16orf71 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf71-to-partner and partner-to-C16orf71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GGTLC2 grouped by C16orf71-low versus C16orf71-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf71→partner) and Y-score (partner→C16orf71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GGTLC2 →	+0.022	+3.103	.001	.004	3	1
SKIN	PAX4 →	+0.019	+3.297	<.001	.002	3	1
SKIN	SYT10 →	+0.295	+3.217	<.001	.006	3	1
SKIN	KCNT2 →	+0.838	+3.304	<.001	.008	3	1
SKIN	CCDC8 →	+1.666	+3.304	.001	.008	3	1
SKIN	OR1L3 →	+0.017	+4.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

GGTLC2 by C16orf71 expression — SKIN

Explore this box plot interactively →