C16orf70

Across TCGA cell cohorts, C16orf70 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C16orf70-associated genes across cancer lineages are IFNG, SPATA19, and DEFB4A. Each is linked with C16orf70 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf70-to-partner and partner-to-C16orf70 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNG grouped by C16orf70-low versus C16orf70-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf70→partner) and Y-score (partner→C16orf70) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IFNG →	+0.233	+4.152	<.001	.009	3	1
BLOOD_Leukemia	SPATA19 →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	DEFB4A →	+0.123	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	OR6B3 →	+0.016	+4.539	<.001	.007	3	1
BLOOD_Leukemia	TRIM49B →	+0.158	+4.874	<.001	.002	3	1
BLOOD_Leukemia	TMEM244 →	+0.416	+4.551	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

IFNG by C16orf70 expression — BLOOD_Leukemia

Explore this box plot interactively →