Across TCGA cell cohorts, C16orf54 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C16orf54-associated genes across cancer lineages are NKX2-6, IQCF5, and TLE7. Each is linked with C16orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C16orf54-to-partner and partner-to-C16orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C16orf54→partner) and Y-score (partner→C16orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.042	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

C16orf54 survival (RNA) · tumor vs normal (RNA) · all C16orf54 data types