Across TCGA patient cohorts, C15orf62 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C15orf62-associated genes across cancer lineages are CDK1, PEA-15_pS116, and Shc_pY317. Each is linked with C15orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C15orf62-to-partner and partner-to-C15orf62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf62→partner) and Y-score (partner→C15orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.176	+2.820	.016	.035	3	2
UCEC	PEA-15_pS116 →	+0.419	+2.459	.013	.020	3	1
UCEC	Shc_pY317 →	-0.319	-3.584	<.001	.002	3	1
UCEC	ARID1A →	-0.193	-3.452	.035	.005	3	1
UCEC	4E-BP1 →	+0.493	+3.584	<.001	.002	3	1
UCEC	ERK2 →	+0.302	+2.459	.001	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

C15orf62 survival (RNA) · tumor vs normal (RNA) · all C15orf62 data types