C15orf48

Across TCGA pan-cancer cohorts, C15orf48 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated C15orf48 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher C15orf48 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C15orf48 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

GBM, LUAD, and UCEC are the cancer types where C15orf48 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	0.386	0.711	.012	7	view →
LUAD	DFS	Quartile	III,IV	1.000	0.400	.008	6	view →
UCEC	OS	Median	All	0.865	0.960	.040	4	view →
LSCC	DFS	Median	II,III,IV	0.970	0.860	.035	3	view →
CCRCC	OS	Median	IV	1.000	0.451	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

C15orf48–GBM (OS)

Open the GBM breakdown →