C15orf48

Across TCGA patient cohorts, C15orf48 mutation is significantly associated with the RNA expression of many other genes, with 135 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C15orf48-associated genes across cancer lineages are RNU7-110P, INCENP, and UBE2Z. Each is linked with C15orf48 in more than 1 cancer types. Because this analysis shows association rather than direction, both C15orf48-to-partner and partner-to-C15orf48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-110P grouped by C15orf48-low versus C15orf48-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf48→partner) and Y-score (partner→C15orf48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-110P →	+0.488	+2.701	.006	.009	3	2
UCEC	INCENP →	+0.864	+3.201	.005	.009	3	1
UCEC	UBE2Z →	+0.550	+3.223	.007	.009	3	1
UCEC	PLK1 →	+1.022	+3.191	.003	.009	3	1
UCEC	ATXN2L →	+0.860	+3.212	<.001	.009	3	1
UCEC	RCE1 →	+0.510	+3.245	.009	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 135 associations by consensus.

RNU7-110P by C15orf48 expression — UCEC

Explore this box plot interactively →