C15orf39

Across TCGA pan-cancer cohorts, C15orf39 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C15orf39 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher C15orf39 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C15orf39 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where C15orf39 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.540	1.000	.008	24	view →
PDAC	OS	Quartile	II,III,IV	0.303	0.691	.005	21	view →
GBM	OS	Median	All	0.883	0.388	.035	2	view →
LUAD	OS	Median	II,III,IV	0.998	0.864	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C15orf39–CCRCC (DFS)

Open the CCRCC breakdown →