C15orf39

Across TCGA patient cohorts, C15orf39 mutation is significantly associated with the RNA expression of many other genes, with 3,306 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C15orf39-associated genes across cancer lineages are MRPS15, RNA5SP360, and CIRBP-AS1. Each is linked with C15orf39 in more than 3 cancer types. Because this analysis shows association rather than direction, both C15orf39-to-partner and partner-to-C15orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPS15 grouped by C15orf39-low versus C15orf39-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf39→partner) and Y-score (partner→C15orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPS15 →	+0.300	+2.457	.007	.001	3	4
SKCM	RNA5SP360 →	+0.073	+4.421	<.001	.003	3	3
UCEC	CIRBP-AS1 →	+0.656	+2.768	<.001	<.001	3	3
UCEC	COX15 →	+0.421	+1.836	<.001	.001	3	3
UCEC	PTS →	+0.307	+3.928	.004	<.001	3	3
UCEC	HAUS1 →	+0.438	+2.606	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,306 associations by consensus.

MRPS15 by C15orf39 expression — UCEC

Explore this box plot interactively →