C15orf39

Across TCGA patient cohorts, C15orf39 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C15orf39-associated genes across cancer lineages are ASNS, PRDX1, and MEK1. Each is linked with C15orf39 in more than 2 cancer types. Because this analysis shows association rather than direction, both C15orf39-to-partner and partner-to-C15orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by C15orf39-low versus C15orf39-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf39→partner) and Y-score (partner→C15orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.732	+3.000	<.001	.034	3	3
UCEC	PRDX1 →	+0.151	+1.584	.028	.009	3	3
UCEC	MEK1 →	+0.364	+2.584	.002	.001	3	2
COAD	14-3-3_epsilon →	+0.165	+3.025	.006	.018	3	2
UCEC	Annexin-1 →	+0.538	+1.926	.002	.008	3	2
COAD	Stathmin →	+0.225	+2.178	.001	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

ASNS by C15orf39 expression — COAD

Explore this box plot interactively →