C15orf39

Across TCGA cell cohorts, C15orf39 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,172 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C15orf39-associated GO terms across cancer lineages are Negative regulation of defense response, Regulation of glial cell proliferation, and Negative regulation of protein-containing complex assembly. Each is linked with C15orf39 in more than 9 cancer types. Because this analysis shows association rather than direction, both C15orf39-to-partner and partner-to-C15orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of defense response grouped by C15orf39-low versus C15orf39-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf39→partner) and Y-score (partner→C15orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of defense response →	+0.073	+0.899	.003	.003	3	10
BLOOD_Leukemia	Regulation of glial cell proliferation →	+0.051	+0.471	.003	.001	3	10
URINARY_TRACT	Negative regulation of protein-containing complex assembly →	+0.074	+1.016	.002	.004	3	10
LARGE_INTESTINE	Regulation of protein localization to nucleus →	+0.075	+1.038	<.001	<.001	3	10
BONE	Negative regulation of RNA splicing →	+0.109	+0.892	.004	<.001	3	10
OVARY	Negative regulation of canonical NF-kappaB signal transduction →	+0.065	+0.903	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,172 associations by consensus.

Negative regulation of defense response by C15orf39 expression — BREAST

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