C15orf39

Across TCGA cell cohorts, C15orf39 mutation is significantly associated with the RNA expression of many other genes, with 360 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C15orf39-associated genes across cancer lineages are SFT2D3, PRAMEF17, and FTMT. Each is linked with C15orf39 in more than 1 cancer types. Because this analysis shows association rather than direction, both C15orf39-to-partner and partner-to-C15orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SFT2D3 grouped by C15orf39-low versus C15orf39-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C15orf39→partner) and Y-score (partner→C15orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SFT2D3 →	+0.634	+4.321	<.001	<.001	3	2
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	2
SOFT_TISSUE	FTMT →	+0.043	+3.977	<.001	.007	3	1
SOFT_TISSUE	ORM1 →	+1.098	+3.607	<.001	.006	3	1
BLOOD_Leukemia	GML →	+0.067	+4.152	.001	.009	3	1
BLOOD_Leukemia	MMP27 →	+0.019	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 360 associations by consensus.

SFT2D3 by C15orf39 expression — SOFT_TISSUE

Explore this box plot interactively →