C14orf39

Across TCGA patient cohorts, C14orf39 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,094 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C14orf39-associated GO terms across cancer lineages are Regulation of translational initiation, Peptidyl-lysine modification, and Negative regulation of RNA splicing. Each is linked with C14orf39 in more than 22 cancer types. Because this analysis shows association rather than direction, both C14orf39-to-partner and partner-to-C14orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by C14orf39-low versus C14orf39-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf39→partner) and Y-score (partner→C14orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of translational initiation →	+0.063	+0.261	.001	.002	3	23
ESCA	Peptidyl-lysine modification →	+0.060	+0.285	<.001	<.001	3	23
ESCA	Negative regulation of RNA splicing →	+0.054	+0.255	.003	.001	3	23
ESCA	Regulation of post-translational protein modification →	+0.063	+0.285	<.001	.001	3	22
ESCA	Regulation of mRNA processing →	+0.067	+0.247	.001	.002	3	22
ESCA	Translational initiation →	+0.066	+0.262	.001	.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,094 associations by consensus.

Regulation of translational initiation by C14orf39 expression — ESCA

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