C14orf39

Across TCGA cell cohorts, C14orf39 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,863 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C14orf39-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Positive regulation of heterotypic cell-cell adhesion, and Negative regulation of myoblast fusion. Each is linked with C14orf39 in more than 5 cancer types. Because this analysis shows association rather than direction, both C14orf39-to-partner and partner-to-C14orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by C14orf39-low versus C14orf39-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf39→partner) and Y-score (partner→C14orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.065	+0.952	<.001	<.001	3	6
BONE	Positive regulation of heterotypic cell-cell adhesion →	-1.056	-0.901	.002	.006	3	5
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.067	+0.958	<.001	<.001	2	6
BLOOD_Leukemia	Mitotic DNA replication →	+0.062	+0.694	.002	.003	3	5
PANCREAS	Positive regulation of cytoplasmic translational initiation →	+0.111	+0.059	<.001	.007	3	5
BLOOD_Leukemia	Regulation of ER to Golgi vesicle-mediated transport →	+0.054	+0.771	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,863 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by C14orf39 expression — BLOOD_Leukemia

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