C14orf39

Across TCGA cell cohorts, C14orf39 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C14orf39-associated genes across cancer lineages are REG1B, CGB3, and OR13C7. Each is linked with C14orf39 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf39-to-partner and partner-to-C14orf39 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by C14orf39-low versus C14orf39-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf39→partner) and Y-score (partner→C14orf39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	1
BLOOD_Leukemia	CGB3 →	+0.026	+3.705	.004	.007	3	1
BLOOD_Leukemia	OR13C7 →	+0.013	+4.384	<.001	.006	3	1
SKIN	CETN1 →	+0.013	+6.022	<.001	.001	3	1
SKIN	OR56A1 →	+0.019	+4.977	<.001	.007	3	1
SKIN	CCDC172 →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

REG1B by C14orf39 expression — BREAST

Explore this box plot interactively →