Across TCGA cell cohorts, C14orf178 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C14orf178-associated genes across cancer lineages are CETN1, OR56A1, and CCDC172. Each is linked with C14orf178 in more than 1 cancer types. Because this analysis shows association rather than direction, both C14orf178-to-partner and partner-to-C14orf178 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C14orf178→partner) and Y-score (partner→C14orf178) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CETN1 →	+0.013	+6.022	<.001	.001	3	1
SKIN	OR56A1 →	+0.019	+4.977	<.001	.007	3	1
SKIN	CCDC172 →	+0.006	+5.415	<.001	.004	3	1
SKIN	CYLC1 →	+0.013	+5.415	<.001	.004	3	1
SKIN	IL31 →	+0.025	+4.977	<.001	.007	3	1
SKIN	SMIM36 →	+0.204	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

C14orf178 survival (RNA) · tumor vs normal (RNA) · all C14orf178 data types