Across TCGA pan-cancer cohorts, C12orf77 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C12orf77 data layer compared with 18 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher C12orf77 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C12orf77 expression acts as an unfavorable survival marker.

ACC and LUSC are the cancer types where C12orf77 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.066	0.667	.002	12	view →
LUSC	DFS	Median	All	0.139	0.707	.022	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: C12orf77 tumor-vs-normal RNA expression · all C12orf77 data types