Across TCGA patient cohorts, C12orf73 protein abundance is significantly associated with the RNA expression of many other genes, with 11,648 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf73-associated genes across cancer lineages are CXCL12, CNRIP1, and MEF2C. Each is linked with C12orf73 in more than 4 cancer types. Because this analysis shows association rather than direction, both C12orf73-to-partner and partner-to-C12orf73 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf73→partner) and Y-score (partner→C12orf73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CXCL12 →	-1.057	-0.426	.001	<.001	3	5
UCEC	CNRIP1 →	-0.860	-0.455	<.001	.001	3	5
OV	MEF2C →	-0.894	-0.824	<.001	<.001	3	5
LUAD	RITA1 →	+0.505	+0.471	<.001	<.001	3	4
UCEC	PTGFR →	-1.216	-0.551	.001	<.001	3	4
UCEC	CNN1 →	-2.174	-0.375	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,648 associations by consensus.

Exploration

C12orf73 survival (RNA) · tumor vs normal (RNA) · all C12orf73 data types