C12orf66

Across TCGA patient cohorts, C12orf66 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,032 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf66-associated proteins across cancer lineages are PARN, XPOT, and UTP18. Each is linked with C12orf66 in more than 5 cancer types. Because this analysis shows association rather than direction, both C12orf66-to-partner and partner-to-C12orf66 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf66 versus PARN in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf66→partner) and Y-score (partner→C12orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARN →	+0.272	+0.618	.003	<.001	3	6
LSCC	XPOT →	+0.523	+0.816	<.001	<.001	3	6
HNSC	UTP18 →	+0.271	+0.548	<.001	<.001	3	5
HNSC	SPCS3 →	-0.441	-0.569	.001	.003	3	5
PDAC	SPR_S103 →	+0.660	+0.296	.001	.001	3	5
LSCC	CFAP36 →	+0.363	+0.641	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,032 associations by consensus.

C12orf66 vs PARN — OV

Explore this scatter interactively →