C12orf66

Across TCGA patient cohorts, C12orf66 mutation is significantly associated with the RNA expression of many other genes, with 4,597 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C12orf66-associated genes across cancer lineages are MIR6803, RNA5SP264, and RNU1-31P. Each is linked with C12orf66 in more than 2 cancer types. Because this analysis shows association rather than direction, both C12orf66-to-partner and partner-to-C12orf66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by C12orf66-low versus C12orf66-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf66→partner) and Y-score (partner→C12orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.098	+4.156	<.001	.004	3	3
LUAD	RNA5SP264 →	+0.249	+4.712	.001	<.001	3	2
SKCM	RNU1-31P →	+0.231	+5.513	<.001	.004	3	2
LUAD	HBZP1 →	+0.060	+5.333	<.001	.001	3	2
CESC	ANKRD26P2 →	+0.057	+5.418	<.001	.005	3	2
SKCM	OOSP1P1 →	+0.212	+5.680	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,597 associations by consensus.

MIR6803 by C12orf66 expression — UCEC

Explore this box plot interactively →