C12orf66

Across TCGA cell cohorts, C12orf66 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,857 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C12orf66-associated GO terms across cancer lineages are Angiogenesis, Mismatch repair, and Regulation of wound healing. Each is linked with C12orf66 in more than 9 cancer types. Because this analysis shows association rather than direction, both C12orf66-to-partner and partner-to-C12orf66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Angiogenesis grouped by C12orf66-low versus C12orf66-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf66→partner) and Y-score (partner→C12orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Angiogenesis →	-0.150	-1.031	<.001	<.001	3	10
BONE	Mismatch repair →	+0.101	+0.675	.001	.006	3	10
BONE	Regulation of wound healing →	-0.105	-0.715	.001	<.001	3	10
BONE	Regulation of blood pressure →	-0.119	-0.803	.002	<.001	3	9
BREAST	Cap-dependent translational initiation →	+0.098	+0.728	<.001	.001	3	9
BONE	Extracellular matrix organization →	-0.152	-0.632	.002	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,857 associations by consensus.

Angiogenesis by C12orf66 expression — BONE

Explore this box plot interactively →