C12orf66

Across TCGA cell cohorts, C12orf66 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible C12orf66-associated genes across cancer lineages are CABP5, ODF1, and OR2M4. Each is linked with C12orf66 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf66-to-partner and partner-to-C12orf66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABP5 grouped by C12orf66-low versus C12orf66-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf66→partner) and Y-score (partner→C12orf66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CABP5 →	+0.016	+4.867	<.001	.009	3	1
OVARY	ODF1 →	+0.015	+4.807	<.001	.003	3	1
OVARY	OR2M4 →	+0.078	+4.700	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CABP5 by C12orf66 expression — BLOOD_Lymphoma

Explore this box plot interactively →