C12orf65

Across TCGA patient cohorts, C12orf65 protein abundance is significantly associated with the RNA expression of many other genes, with 5,699 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf65-associated genes across cancer lineages are PEAR1, TRAV3, and MIR145. Each is linked with C12orf65 in more than 2 cancer types. Because this analysis shows association rather than direction, both C12orf65-to-partner and partner-to-C12orf65 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf65 versus PEAR1 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf65→partner) and Y-score (partner→C12orf65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PEAR1 →	-0.627	-0.357	<.001	.001	3	3
OV	TRAV3 →	-0.884	-0.963	.004	.002	3	3
OV	MIR145 →	-1.495	-0.873	.003	.003	3	3
BRCA	MINCR →	+1.146	+0.379	<.001	<.001	3	3
OV	IFITM2 →	-1.480	-1.123	.003	<.001	3	3
OV	PPP6R2 →	-0.426	-0.617	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,699 associations by consensus.

C12orf65 vs PEAR1 — LSCC

Explore this scatter interactively →