C12orf65

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, C12orf65 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C12orf65-associated genes across cancer lineages are HSFY2. Each is linked with C12orf65 in more than 1 cancer types. Because this analysis shows association rather than direction, both C12orf65-to-partner and partner-to-C12orf65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HSFY2 grouped by C12orf65-low versus C12orf65-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf65→partner) and Y-score (partner→C12orf65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEHSFY2 →+0.023+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

HSFY2 by C12orf65 expression — LARGE_INTESTINE

Box plot of HSFY2 in C12orf65-low vs C12orf65-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration