C12orf45

Across TCGA patient cohorts, C12orf45 protein abundance is significantly associated with the RNA expression of many other genes, with 8,814 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C12orf45-associated genes across cancer lineages are STOM, PBLD, and RFC5. Each is linked with C12orf45 in more than 4 cancer types. Because this analysis shows association rather than direction, both C12orf45-to-partner and partner-to-C12orf45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf45 versus STOM in LSCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf45→partner) and Y-score (partner→C12orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STOM →	-0.665	-0.304	<.001	<.001	3	5
CCRCC	PBLD →	-0.762	-0.245	.006	.001	3	4
LSCC	RFC5 →	+0.571	+0.272	.003	.003	3	4
BRCA	ITPR1 →	-0.540	-0.217	.004	.005	3	4
BRCA	SYNC →	-0.845	-0.337	<.001	.001	3	4
LSCC	PARPBP →	+0.681	+0.316	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,814 associations by consensus.

C12orf45 vs STOM — LSCC

Explore this scatter interactively →