C12orf45

Across TCGA cell cohorts, C12orf45 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,988 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C12orf45-associated GO terms across cancer lineages are tRNA 5'-end processing, Protein import into mitochondrial intermembrane space, and Process utilizing autophagic mechanism. Each is linked with C12orf45 in more than 13 cancer types. Because this analysis shows association rather than direction, both C12orf45-to-partner and partner-to-C12orf45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-end processing grouped by C12orf45-low versus C12orf45-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf45→partner) and Y-score (partner→C12orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA 5'-end processing →	+0.140	+0.843	.001	.002	2	14
BLOOD_Myeloma	Protein import into mitochondrial intermembrane space →	+0.153	+1.123	.002	<.001	3	13
URINARY_TRACT	Process utilizing autophagic mechanism →	-0.038	-0.775	<.001	.002	3	12
URINARY_TRACT	Autophagy →	-0.038	-0.775	<.001	.002	3	12
SKIN	Negative regulation of amyloid precursor protein catabolic process →	-0.118	-0.601	<.001	.001	3	12
BLOOD_Myeloma	Mitochondrial disulfide relay system →	+0.151	+1.123	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,988 associations by consensus.

tRNA 5'-end processing by C12orf45 expression — BONE

Explore this box plot interactively →