C12orf43

Across TCGA patient cohorts, C12orf43 protein abundance is significantly associated with the RNA expression of many other genes, with 9,860 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C12orf43-associated genes across cancer lineages are NAT10, NUDT1, and SRSF9. Each is linked with C12orf43 in more than 6 cancer types. Because this analysis shows association rather than direction, both C12orf43-to-partner and partner-to-C12orf43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C12orf43 versus NAT10 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf43→partner) and Y-score (partner→C12orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NAT10 →	+0.693	+0.232	<.001	.003	3	7
UCEC	NUDT1 →	+0.971	+0.260	<.001	<.001	3	6
UCEC	SRSF9 →	+0.599	+0.238	.001	.001	3	6
UCEC	SNRPF →	+0.929	+0.233	<.001	<.001	3	6
COAD	TRIAP1 →	+0.815	+0.704	<.001	<.001	3	6
UCEC	KNTC1 →	+0.673	+0.302	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,860 associations by consensus.

C12orf43 vs NAT10 — HNSC

Explore this scatter interactively →