C12orf4

Across TCGA cell cohorts, C12orf4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,605 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C12orf4-associated GO terms across cancer lineages are Nuclear division, Positive regulation of cell cycle, and Positive regulation of cell cycle process. Each is linked with C12orf4 in more than 15 cancer types. Because this analysis shows association rather than direction, both C12orf4-to-partner and partner-to-C12orf4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear division grouped by C12orf4-low versus C12orf4-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C12orf4→partner) and Y-score (partner→C12orf4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Nuclear division →	+0.076	+0.725	<.001	<.001	3	16
PANCREAS	Positive regulation of cell cycle →	+0.059	+0.821	.001	<.001	3	16
PANCREAS	Positive regulation of cell cycle process →	+0.078	+0.813	<.001	<.001	3	16
SOFT_TISSUE	Regulation of chromosome condensation →	+0.189	+0.683	<.001	.002	3	15
PANCREAS	Positive regulation of mitotic cell cycle →	+0.074	+0.728	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid segregation →	+0.096	+0.710	.005	.009	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,605 associations by consensus.

Nuclear division by C12orf4 expression — CNS

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