C11orf98

Across TCGA cell cohorts, C11orf98 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,376 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C11orf98-associated GO terms across cancer lineages are mRNA modification, Mitochondrial electron transport, succinate to ubiquinone, and DNA replication initiation. Each is linked with C11orf98 in more than 12 cancer types. Because this analysis shows association rather than direction, both C11orf98-to-partner and partner-to-C11orf98 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA modification grouped by C11orf98-low versus C11orf98-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf98→partner) and Y-score (partner→C11orf98) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA modification →	+0.079	+0.777	<.001	<.001	3	13
LIVER	Mitochondrial electron transport, succinate to ubiquinone →	+0.109	+0.938	<.001	<.001	2	13
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.169	+0.772	.003	.004	2	13
BONE	Asparaginyl-tRNA aminoacylation →	+0.134	+0.711	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.209	+0.892	<.001	.001	3	12
BONE	tRNA wobble uridine modification →	+0.075	+0.678	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,376 associations by consensus.

mRNA modification by C11orf98 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →