C11orf97

Across TCGA cell cohorts, C11orf97 RNA expression is significantly associated with the go_rna of many other GO terms, with 488 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf97-associated GO terms across cancer lineages are Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand, Leukocyte migration, and G1 to G0 transition involved in cell differentiation. Each is linked with C11orf97 in more than 2 cancer types. Because this analysis shows association rather than direction, both C11orf97-to-partner and partner-to-C11orf97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand grouped by C11orf97-low versus C11orf97-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf97→partner) and Y-score (partner→C11orf97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand →	-0.190	-0.018	<.001	.004	3	3
BLOOD_Leukemia	Leukocyte migration →	+0.096	+0.020	<.001	.001	3	3
BLOOD_Leukemia	G1 to G0 transition involved in cell differentiation →	+0.740	+0.020	.007	.001	3	3
LUNG_NSCLC_LUAD	Desmosome assembly →	+0.155	+0.051	.004	.007	3	2
LUNG_NSCLC_LUAD	Positive regulation of heart contraction →	-0.089	-0.040	.004	.003	3	2
LUNG_NSCLC_LUAD	DNA modification →	-0.058	-0.073	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 488 associations by consensus.

Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand by C11orf97 expression — BLOOD_Leukemia

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