Across TCGA pan-cancer cohorts, C11orf95 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C11orf95 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher C11orf95 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C11orf95 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, CCRCC, and HNSC are the cancer types where C11orf95 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	All	0.938	0.711	.018	6	view →
CCRCC	DFS	Tertile	III,IV	1.000	0.328	.017	4	view →
HNSC	DFS	Quartile	III,IV	0.901	0.594	.033	3	view →
LUAD	DFS	Median	All	0.481	1.000	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: C11orf95 tumor-vs-normal RNA expression · all C11orf95 data types