C11orf91

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C11orf91 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated C11orf91 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C11orf91 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C11orf91 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

LUAD, READ, and COAD are the cancer types where C11orf91 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSMedianAll0.6020.720<.00164view →
READDFSMedianIII,IV0.7580.412<.00141view →
COADOSMedianII,III,IV0.4470.659.00240view →
STADDFSTertileII,III,IV0.3800.609.00431view →
LGGDFSTertileAll0.7200.891<.00130view →
LUSCDFSMedianII,III,IV0.6060.869.00327view →
GBMDFSTertileAll0.1520.275.00226view →
SKCMOSTertileIII,IV0.5310.232<.00126view →
UCECDFSTertileIV0.8320.391.00724view →
MESOOSTertileAll0.4580.674.01321view →
TGCTDFSQuartileAll0.5810.863.00420view →
KIRCDFSQuartileIII,IV0.2890.544.00619view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration