C11orf87

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C11orf87 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf87-associated genes across cancer lineages are Caspase-7-cleavedD198, EGFR_pY1068, and GAPDH. Each is linked with C11orf87 in more than 2 cancer types. Because this analysis shows association rather than direction, both C11orf87-to-partner and partner-to-C11orf87 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf87→partner) and Y-score (partner→C11orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaspase-7-cleavedD198 →+0.428+2.019.037.01733
COADEGFR_pY1068 →-0.478-3.000.003.03432
COADGAPDH →+0.661+3.012.008.01832
UCECJNK_pT183_Y185 →-0.186-2.115.001.01732
UCECMEK1 →+0.340+2.070.007.00132
UCECp62 Lck ligand →+0.353+2.070.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration