Across TCGA cell cohorts, C11orf87 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C11orf87-associated genes across cancer lineages are IQCF5, OC90, and CCDC182. Each is linked with C11orf87 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf87-to-partner and partner-to-C11orf87 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf87→partner) and Y-score (partner→C11orf87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	IQCF5 →	+0.104	+5.201	<.001	.006	3	1
BLOOD_Leukemia	OC90 →	+0.013	+5.201	<.001	.006	3	1
LARGE_INTESTINE	CCDC182 →	+0.043	+3.632	<.001	.003	3	1
LARGE_INTESTINE	OR2D3 →	+0.033	+3.510	<.001	.003	3	1
LARGE_INTESTINE	KLHL14 →	+0.179	+3.554	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

C11orf87 survival (RNA) · tumor vs normal (RNA) · all C11orf87 data types