Q-omics provides the consensus-scored C11orf72 profile across patient tissues and cancer cell-line models. C11orf72 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, C11orf72 is differentially expressed in 13, with the highest sampling consensus in KIRC. Additionally, C11orf72 RNA expression shows 12,464 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UCEC, KIRC, and ACC as cancer lineages where C11orf72 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for C11orf72 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes C11orf72 survival associations across molecular data types. C11orf72 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible C11orf72 RNA expression–survival associations across cancer types. High C11orf72 expression shows unfavorable associations in UCEC, THYM, BRCA and COAD, but favorable associations in LUAD and LGG. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for C11orf72 RNA expression.
This table summarizes C11orf72 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for C11orf72. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. C11orf72 shows lower tumor expression in KIRC and KIRP and higher tumor expression in BLCA, HNSC, LUSC and COAD. The KIRC box plot shows higher C11orf72 RNA expression in normal versus tumor tissue (log2 FC = −0.176, t-test p < 0.001).
This table shows molecular features associated with C11orf72 in patient tissues and cancer cell lines. In patient samples, C11orf72 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
