C11orf68

Across TCGA patient cohorts, C11orf68 mutation is significantly associated with the RNA expression of many other genes, with 412 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf68-associated genes across cancer lineages are RPL22P6, HSPE1-MOB4, and BNIP3P4. Each is linked with C11orf68 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf68-to-partner and partner-to-C11orf68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL22P6 grouped by C11orf68-low versus C11orf68-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf68→partner) and Y-score (partner→C11orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL22P6 →	+0.074	+3.641	<.001	.002	3	2
UCEC	HSPE1-MOB4 →	+0.209	+2.629	<.001	.003	3	1
UCEC	BNIP3P4 →	+0.095	+3.484	<.001	.001	3	1
UCEC	TAF9 →	+0.639	+3.191	.001	.009	3	1
UCEC	IGHV4-4 →	+1.634	+2.783	<.001	.002	3	1
UCEC	HNRNPCL3 →	+0.065	+2.708	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 412 associations by consensus.

RPL22P6 by C11orf68 expression — UCEC

Explore this box plot interactively →