C11orf68

Across TCGA patient cohorts, C11orf68 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf68-associated genes across cancer lineages are ACC_pS79, ACC1, and Ku80. Each is linked with C11orf68 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf68-to-partner and partner-to-C11orf68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACC_pS79 grouped by C11orf68-low versus C11orf68-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf68→partner) and Y-score (partner→C11orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.482	+3.009	.011	.019	3	1
UCEC	ACC1 →	+0.560	+3.169	.004	.020	3	1
UCEC	Ku80 →	+0.318	+3.183	.014	.010	3	1
UCEC	eIF4G →	+0.383	+3.169	.024	.020	1	1
UCEC	MSH6 →	+0.366	+3.169	.043	.020	1	1
UCEC	Cyclin-E2 →	+0.206	+3.169	.026	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ACC_pS79 by C11orf68 expression — UCEC

Explore this box plot interactively →