C11orf68

Across TCGA cell cohorts, C11orf68 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,020 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C11orf68-associated GO terms across cancer lineages are Regulation of protein K48-linked ubiquitination, Regulation of cell communication by electrical coupling, and Positive regulation of establishment of T cell polarity. Each is linked with C11orf68 in more than 15 cancer types. Because this analysis shows association rather than direction, both C11orf68-to-partner and partner-to-C11orf68 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K48-linked ubiquitination grouped by C11orf68-low versus C11orf68-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf68→partner) and Y-score (partner→C11orf68) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of protein K48-linked ubiquitination →	+0.136	+1.000	<.001	<.001	3	16
LIVER	Regulation of cell communication by electrical coupling →	+0.286	+1.393	<.001	<.001	3	15
LIVER	Positive regulation of establishment of T cell polarity →	+0.275	+1.832	<.001	<.001	3	15
BONE	Negative regulation of Rho protein signal transduction →	+0.182	+1.178	<.001	<.001	3	15
LUNG_NSCLC_LUSC	PML body organization →	+0.300	+2.267	<.001	<.001	3	14
URINARY_TRACT	Negative regulation of receptor signaling pathway via STAT →	+0.144	+1.632	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,020 associations by consensus.

Regulation of protein K48-linked ubiquitination by C11orf68 expression — OVARY

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