C11orf65

Across TCGA patient cohorts, C11orf65 mutation is significantly associated with the RNA expression of many other genes, with 1,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf65-associated genes across cancer lineages are RPSAP35, MED28P4, and MIR4774. Each is linked with C11orf65 in more than 2 cancer types. Because this analysis shows association rather than direction, both C11orf65-to-partner and partner-to-C11orf65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPSAP35 grouped by C11orf65-low versus C11orf65-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf65→partner) and Y-score (partner→C11orf65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPSAP35 →	+0.054	+6.902	<.001	<.001	3	3
READ	MED28P4 →	+0.394	+5.039	<.001	.008	3	2
READ	MIR4774 →	+0.841	+6.257	<.001	.001	3	2
COAD	MIR3135A →	+0.882	+4.602	<.001	.008	3	2
UCEC	RNA5SP113 →	+0.353	+3.003	<.001	.007	3	2
UCEC	IPO7P1 →	+0.361	+2.217	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,381 associations by consensus.

RPSAP35 by C11orf65 expression — LIHC

Explore this box plot interactively →