C11orf65

Across TCGA cell cohorts, C11orf65 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,411 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf65-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Transcription preinitiation complex assembly, and Pyruvate decarboxylation to acetyl-CoA. Each is linked with C11orf65 in more than 7 cancer types. Because this analysis shows association rather than direction, both C11orf65-to-partner and partner-to-C11orf65 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium movement involved in cell motility grouped by C11orf65-low versus C11orf65-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf65→partner) and Y-score (partner→C11orf65) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cilium movement involved in cell motility →	-0.062	-0.450	<.001	<.001	3	7
BLOOD_Leukemia	Transcription preinitiation complex assembly →	+0.050	+0.346	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Pyruvate decarboxylation to acetyl-CoA →	+0.141	+0.459	<.001	<.001	3	7
LIVER	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.098	+0.381	.002	.009	2	8
CNS	Vesicle targeting, rough ER to cis-Golgi →	+0.090	+0.462	<.001	.001	3	7
LUNG_NSCLC_LUAD	Cilium or flagellum-dependent cell motility →	-0.055	-0.470	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,411 associations by consensus.

Cilium movement involved in cell motility by C11orf65 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →