C11orf58

Across TCGA patient cohorts, C11orf58 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,577 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C11orf58-associated proteins across cancer lineages are TSG101, PIK3C2A, and USP47. Each is linked with C11orf58 in more than 3 cancer types. Because this analysis shows association rather than direction, both C11orf58-to-partner and partner-to-C11orf58 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf58 versus TSG101 in PDAC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf58→partner) and Y-score (partner→C11orf58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TSG101 →	+0.259	+0.270	<.001	<.001	3	4
OV	PIK3C2A →	+0.314	+0.629	<.001	<.001	3	4
LUAD	USP47 →	+0.190	+0.264	.001	.001	3	4
LSCC	CLASP1 →	+0.230	+0.375	.007	.003	3	3
COAD	GSTK1 →	-0.412	-0.387	.003	<.001	3	3
GBM	HMGCL →	-0.397	-0.338	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,577 associations by consensus.

C11orf58 vs TSG101 — PDAC

Explore this scatter interactively →