Across TCGA patient cohorts, C11orf54 protein abundance is significantly associated with the RNA expression of many other genes, with 11,865 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C11orf54-associated genes across cancer lineages are BTD, KBTBD3, and KPNA2. Each is linked with C11orf54 in more than 5 cancer types. Because this analysis shows association rather than direction, both C11orf54-to-partner and partner-to-C11orf54 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf54→partner) and Y-score (partner→C11orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BTD →	+0.573	+0.274	<.001	.004	3	6
CCRCC	KBTBD3 →	+0.426	+0.387	.001	.002	3	6
BRCA	KPNA2 →	-0.859	-0.427	<.001	<.001	3	6
LUAD	CDKN3 →	-0.741	-0.306	<.001	<.001	3	5
BRCA	CENPI →	-0.822	-0.301	<.001	.003	3	5
BRCA	CCNE1 →	-1.314	-0.299	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,865 associations by consensus.

Exploration

C11orf54 survival (RNA) · tumor vs normal (RNA) · all C11orf54 data types