Across TCGA patient cohorts, C11orf54 mutation is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf54-associated genes across cancer lineages are RNU5A-2P, RNU6ATAC25P, and RN7SKP169. Each is linked with C11orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf54-to-partner and partner-to-C11orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf54→partner) and Y-score (partner→C11orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU5A-2P →	+0.418	+5.003	<.001	.004	3	1
COAD	RNU6ATAC25P →	+0.309	+5.917	<.001	.001	3	1
COAD	RN7SKP169 →	+0.214	+5.392	<.001	.002	3	1
COAD	RPL18P1 →	+0.425	+5.542	<.001	<.001	3	1
COAD	RNU6-781P →	+0.341	+5.122	<.001	.004	3	1
COAD	LINC02317 →	+0.155	+5.122	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

Exploration

C11orf54 survival (RNA) · tumor vs normal (RNA) · all C11orf54 data types