Across TCGA patient cohorts, C11orf54 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf54-associated genes across cancer lineages are Di-Ras3, P-Cadherin, and STAT3_pY705. Each is linked with C11orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf54-to-partner and partner-to-C11orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf54→partner) and Y-score (partner→C11orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Di-Ras3 →	-0.148	-2.321	.047	.035	3	2
UCEC	P-Cadherin →	-0.184	-2.308	.011	.036	3	1
UCEC	STAT3_pY705 →	-0.338	-2.321	.010	.035	3	1
UCEC	Tuberin →	+0.342	+2.321	.011	.035	3	1
UCEC	ASNS →	+0.462	+2.321	.011	.035	3	1
UCEC	eEF2K →	+0.356	+3.000	.042	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

C11orf54 survival (RNA) · tumor vs normal (RNA) · all C11orf54 data types