Across TCGA cell cohorts, C11orf54 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C11orf54-associated genes across cancer lineages are KCNA7, SYT10, and LMOD2. Each is linked with C11orf54 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf54-to-partner and partner-to-C11orf54 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf54→partner) and Y-score (partner→C11orf54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNA7 →	+0.198	+2.648	<.001	.008	3	1
LARGE_INTESTINE	SYT10 →	+0.195	+2.518	<.001	.006	3	1
LARGE_INTESTINE	LMOD2 →	+0.106	+3.643	.007	.005	3	1
LARGE_INTESTINE	XCR1 →	+0.274	+3.491	<.001	.006	3	1
LARGE_INTESTINE	LBX2 →	+0.839	+3.241	.005	.007	3	1
LARGE_INTESTINE	FCER1A →	+0.168	+3.770	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

C11orf54 survival (RNA) · tumor vs normal (RNA) · all C11orf54 data types