C11orf53

Across TCGA patient cohorts, C11orf53 protein abundance is significantly associated with the RNA expression of many other genes, with 339 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C11orf53-associated genes across cancer lineages are RTCB, COCH, and PHKB. Each is linked with C11orf53 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf53-to-partner and partner-to-C11orf53 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf53 versus RTCB in PDAC, with a Pearson correlation of -0.97.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf53→partner) and Y-score (partner→C11orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RTCB →	-0.609	-0.544	.006	.007	1	1
PDAC	COCH →	-0.459	-0.544	.006	.007	1	1
PDAC	PHKB →	-0.475	-0.544	.002	.007	1	1
PDAC	CORO2B →	+0.819	+0.544	<.001	.007	1	1
PDAC	BRF2 →	-0.794	-0.544	.006	.007	1	1
PDAC	PIH1D1 →	-0.199	-0.544	.006	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 339 associations by consensus.

C11orf53 vs RTCB — PDAC

Explore this scatter interactively →